Morphological changes of lipid droplets in adipocytes
نویسندگان
چکیده
منابع مشابه
Remodeling of Lipid Droplets during Lipolysis and Growth in Adipocytes*
Synthesis, storage, and turnover of triacylglycerols (TAGs) in adipocytes are critical cellular processes to maintain lipid and energy homeostasis in mammals. TAGs are stored in metabolically highly dynamic lipid droplets (LDs), which are believed to undergo fragmentation and fusion under lipolytic and lipogenic conditions, respectively. Time lapse fluorescence microscopy showed that stimulatio...
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Despite the lipolysis-lipogenesis cycle being a fundamental process in adipocyte biology, very little is known about the morphological changes that occur during this process. The remodeling of lipid droplets to form micro lipid droplets (mLDs) is a striking feature of lipolysis in adipocytes, but once lipolysis ceases, the cell must regain its basal morphology. We characterized mLD formation in...
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– Dynamics of spreading of viscous non volatile fluid droplets on surfaces is modelled using a solid on solid model, which is studied with Monte Carlo simulations. Tendency for dynamical layering and surface attraction are in part embedded into the effective dynamics of the model. This allows a description of the spreading process with a single parameter, which strongly influences the morpholog...
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BACKGROUND Polychlorinated biphenyls (PCBs) are persistent environmental pollutants that preferentially accumulate in lipid-rich tissues of contaminated organisms. Although the adipose tissue constitutes a major intern reservoir of PCBs and recent epidemiological studies associate PCBs to the development of obesity and its related disorders, little is known about the mechanisms involved in thei...
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We report on the heterogeneity and diversity of lipid droplets (LDs) in early stages of adipogenesis by elucidating the cell and molecular biology of amphiphilic and cytoskeletal proteins regulating and stabilizing the generation of LDs in human adipose cells. A plethora of distinct and differently sized LDs was detected by a brief application of adipocyte differentiation medium and additional ...
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ژورنال
عنوان ژورنال: Journal of the Visualization Society of Japan
سال: 2008
ISSN: 0916-4731,1884-037X
DOI: 10.3154/jvs.28.1157